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Dr. Hagit Baris Feldman, M.D.



Prof. Hagit Baris Feldman, M.D., is the Director of the Genetics Institute at Tel Aviv Sourasky Medical Center (TLVMC), where she established the Genomic Center and the Gaucher Disease Center. She is an associate Prof. in Sackler School of Medicine at Tal Aviv University.


Prof. Hagit Baris Feldman graduated from the Sackler Faculy of Medicine, Tel Aviv University, completed her residency in Pediatrics from Sapir Medical Center and completed with honors her Medical Genetics residency from Harvard Medical School – Genetics Training Program.


Prof. Baris Feldman leads Gaucher clinic since 2008 and is involved in clinical research in Gaucher disease including pharmaceutical clinical studies. She is a member of several scientific boards regarding Gaucher disease and lectures in Scientific conferences on this topic.


Prof. Baris Feldman is the Chair of the Israeli Medical Genetics Association, and a member of The American Society of Human Genetics, The European Society of Human Genetics and the Israel Medical Association. She is a member of the editorial board for Human Genetics. Shehas published over 60 original peer reviewed papers and she is involved in the education and training of medical students and fellows in Medical Genetics.



Prof. Baris research group study the genetic basis of human Mendelian syndromes from various medical disciplines using next generation technologies, coupled with functional analyses to uncover novel disease pathways. The laboratory combines genetic, computational and molecular biology methods to study rare diseases and investigate the pathophysiological mechanisms underlying these syndromes, and is collaborating with top experts both in Israel and worldwide.

Over the last five years, Prof. Baris research lab uncovered numerous novel human disease-causing genes using whole exome sequencing. These serve as a first step to better understand human physiology in health and disease, followed by potential application of this knowledge to implement precision medicine and tailored treatments. The discoveries provided personalized genetic counseling for families with rare genetic disorders and promoted the birth of healthy children through prenatal and preimplantation genetic diagnoses. Moreover, the findings paved the way to tailored medical treatment for some of the patients, which became the treatment of choice for similar patients worldwide. The lab's research is patient-driven with the aim of continued implementation of personalized medicine and disease prevention.

Recently, The Baris lab embarked on a new project aimed at identifying risk and protective variants in genes involved in COVID-19 morbidity and disease severity in the hope of identifying in-risk patients and new treatment target targets. The group is taking part in an international consortium aimed at understanding the genetic predisposition to SARS-CoV-2 infection

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